December 31, 2021 Journal article Open Access

John Osei Sekyere; Melese Abate Reta

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    <subfield code="a">Global evolutionary epidemiology and resistome dynamics of Citrobacter species, Enterobacter hormaechei, Klebsiella variicola, and Proteeae clones</subfield>
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    <subfield code="a">&lt;p&gt;&lt;strong&gt;Summary&lt;/strong&gt;&lt;br&gt;
&lt;em&gt;Citrobacter spp., Enterobacter hormaechei subsp.,&amp;nbsp;Klebsiella variicola&lt;/em&gt; and &lt;em&gt;Proteae &lt;/em&gt;tribe members are&amp;nbsp;rarely isolated&amp;nbsp; &lt;em&gt;Enterobacterales&lt;/em&gt; increasingly implicated&amp;nbsp;in nosocomial infections. Herein, we show that&amp;nbsp;these species contain multiple genes encoding resistance&amp;nbsp;to important antibiotics and are widely and&amp;nbsp;globally distributed, being isolated from human, animal,&lt;br&gt;
plant, and environmental sources in 67 countries.&amp;nbsp;Certain clones and clades of these species were&amp;nbsp;internationally disseminated, serving as reservoirs&amp;nbsp;and mediums for the global dissemination of antibiotic&amp;nbsp;resistance genes. As they can easily transmit&lt;br&gt;
these genes to more pathogenic species, additional&amp;nbsp;molecular surveillance studies should be undertaken&amp;nbsp;to identify and contain these antibiotic-resistant&amp;nbsp;species.&lt;/p&gt;</subfield>
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    <subfield code="a">10.1111/1462-2920.15387</subfield>
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