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Global evolutionary epidemiology and resistome dynamics of Citrobacter species, Enterobacter hormaechei, Klebsiella variicola, and Proteeae clones

John Osei Sekyere; Melese Abate Reta


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{
  "description": "<p><strong>Summary</strong><br>\n<em>Citrobacter spp., Enterobacter hormaechei subsp.,&nbsp;Klebsiella variicola</em> and <em>Proteae </em>tribe members are&nbsp;rarely isolated&nbsp; <em>Enterobacterales</em> increasingly implicated&nbsp;in nosocomial infections. Herein, we show that&nbsp;these species contain multiple genes encoding resistance&nbsp;to important antibiotics and are widely and&nbsp;globally distributed, being isolated from human, animal,<br>\nplant, and environmental sources in 67 countries.&nbsp;Certain clones and clades of these species were&nbsp;internationally disseminated, serving as reservoirs&nbsp;and mediums for the global dissemination of antibiotic&nbsp;resistance genes. As they can easily transmit<br>\nthese genes to more pathogenic species, additional&nbsp;molecular surveillance studies should be undertaken&nbsp;to identify and contain these antibiotic-resistant&nbsp;species.</p>", 
  "license": "https://creativecommons.org/licenses/by-nc/4.0/", 
  "creator": [
    {
      "@type": "Person", 
      "name": "John Osei Sekyere"
    }, 
    {
      "@id": "https://orcid.org/0000-0003-1301-4746", 
      "@type": "Person", 
      "name": "Melese Abate Reta"
    }
  ], 
  "headline": "Global evolutionary epidemiology and resistome dynamics of Citrobacter species, Enterobacter hormaechei, Klebsiella variicola, and Proteeae clones", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2021-12-31", 
  "url": "https://nadre.ethernet.edu.et/record/8657", 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.1111/1462-2920.15387", 
  "@id": "https://doi.org/10.1111/1462-2920.15387", 
  "@type": "ScholarlyArticle", 
  "name": "Global evolutionary epidemiology and resistome dynamics of Citrobacter species, Enterobacter hormaechei, Klebsiella variicola, and Proteeae clones"
}
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