December 31, 2021 Journal article Open Access

John Osei Sekyere; Melese Abate Reta

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  <identifier identifierType="URL">https://nadre.ethernet.edu.et/record/8657</identifier>
  <creators>
    <creator>
      <creatorName>John Osei Sekyere</creatorName>
    </creator>
    <creator>
      <creatorName>Melese Abate Reta</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0003-1301-4746</nameIdentifier>
    </creator>
  </creators>
  <titles>
    <title>Global evolutionary epidemiology and resistome dynamics of Citrobacter species, Enterobacter hormaechei, Klebsiella variicola, and Proteeae clones</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-12-31</date>
  </dates>
  <resourceType resourceTypeGeneral="JournalArticle"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://nadre.ethernet.edu.et/record/8657</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1111/1462-2920.15387</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by-nc/4.0/">Creative Commons Attribution-NonCommercial</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;&lt;strong&gt;Summary&lt;/strong&gt;&lt;br&gt;
&lt;em&gt;Citrobacter spp., Enterobacter hormaechei subsp.,&amp;nbsp;Klebsiella variicola&lt;/em&gt; and &lt;em&gt;Proteae &lt;/em&gt;tribe members are&amp;nbsp;rarely isolated&amp;nbsp; &lt;em&gt;Enterobacterales&lt;/em&gt; increasingly implicated&amp;nbsp;in nosocomial infections. Herein, we show that&amp;nbsp;these species contain multiple genes encoding resistance&amp;nbsp;to important antibiotics and are widely and&amp;nbsp;globally distributed, being isolated from human, animal,&lt;br&gt;
plant, and environmental sources in 67 countries.&amp;nbsp;Certain clones and clades of these species were&amp;nbsp;internationally disseminated, serving as reservoirs&amp;nbsp;and mediums for the global dissemination of antibiotic&amp;nbsp;resistance genes. As they can easily transmit&lt;br&gt;
these genes to more pathogenic species, additional&amp;nbsp;molecular surveillance studies should be undertaken&amp;nbsp;to identify and contain these antibiotic-resistant&amp;nbsp;species.&lt;/p&gt;</description>
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