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Prevalence Of Undernutrition And Associated Factors Among Adults Receiving First-Line Antiretroviral Treatment In Public Health Facilities Of Arba Minch Town, Southern Ethiopia

Bilcha Oumer; Negussie Boti; Sultan Hussen; Teklemariam Gultie


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  <identifier identifierType="DOI">10.20372/nadre/4444</identifier>
  <creators>
    <creator>
      <creatorName>Bilcha Oumer</creatorName>
      <affiliation>1Department of Midwifery, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia</affiliation>
    </creator>
    <creator>
      <creatorName>Negussie Boti</creatorName>
      <affiliation>Department of Public Health, College of Medicine a</affiliation>
    </creator>
    <creator>
      <creatorName>Sultan Hussen</creatorName>
      <affiliation>Department of Public Health, College of Medicine a</affiliation>
    </creator>
    <creator>
      <creatorName>Teklemariam Gultie</creatorName>
      <affiliation>1Department of Midwifery, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Prevalence Of Undernutrition And Associated Factors Among Adults Receiving First-Line Antiretroviral Treatment In Public Health Facilities Of Arba Minch Town, Southern Ethiopia</title>
  </titles>
  <publisher>National Academic Digital Repository of Ethiopia</publisher>
  <publicationYear>2019</publicationYear>
  <dates>
    <date dateType="Issued">2019-11-27</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://nadre.ethernet.edu.et/record/4444</alternateIdentifier>
  </alternateIdentifiers>
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    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://nadre.ethernet.edu.et/communities/amumhs</relatedIdentifier>
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  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/odc-by">Open Data Commons Attribution License</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;Introduction: Access to antiretroviral drugs for all infected persons in need is a global&lt;br&gt;
health priority. The primary goals of initiating antiretroviral drugs are to suppress human&lt;br&gt;
immunodeficiency virus viral replication and to restore immune function. However, adequate&lt;br&gt;
nutrition is necessary to manage opportunistic infections and to maintain the immune system.&lt;br&gt;
Therefore, this study aimed to determine the recent prevalence of undernutrition and&lt;br&gt;
associated factors among HIV patients receiving first-line antiretroviral therapy in public&lt;br&gt;
health facilities of Arba Minch town, Gamo zone, Southern Ethiopia.&lt;br&gt;
Methods: Institution-based cross-sectional study was used among 333 adult patients receiving&lt;br&gt;
first-line antiretroviral therapy at public health facilities of Arba Minch town. A simple&lt;br&gt;
random sampling technique was used to select the study subjects. Data were collected&lt;br&gt;
through interviewer-administered questionnaires. Binary and multivariable logistic regression&lt;br&gt;
analyses were used to identify factors associated with undernutrition. A p-value &amp;lt;0.05&lt;br&gt;
with a 95% confidence level was used to declare statistical significance.&lt;br&gt;
Results: The overall prevalence of undernutrition among adult patients receiving first-line&lt;br&gt;
antiretroviral therapy is 23.72% (95% CI: 19.13&amp;ndash;28.27%). Current substance use&lt;br&gt;
(AOR=1.83, 95% CI:1.09&amp;ndash;3.08), duration on antiretroviral therapy (AOR=1.87, 95%&lt;br&gt;
CI:1.06&amp;ndash;3.30), not taking cotrimoxazole preventive therapy (AOR=2.09, 95% CI:1.15&amp;ndash;&lt;br&gt;
3.82), advanced WHO clinical stages (AOR=5.1, 95% CI: 2.9&amp;ndash;7.7), CD4 count less than&lt;br&gt;
350 cell/mm3 (AOR=1.83, 95% CI: 1.09&amp;ndash;3.05) and active tuberculosis (AOR=1.89, 95% CI:&lt;br&gt;
1.02&amp;ndash;3.53) were factors significantly associated with undernutrition among respondents who&lt;br&gt;
were enrolled on first-line antiretroviral therapy.&lt;br&gt;
Conclusion: This study shows that the prevalence of undernutrition was high among adult&lt;br&gt;
patients on first-line antiretroviral therapy. Therefore, this finding shows the need to implement&lt;br&gt;
nutrition programs to improve the nutritional status of adults living with HIV in the study area.&lt;br&gt;
The interventions should emphasise those patients who use the substance, who are in advanced&lt;br&gt;
WHO clinical stage and have active tuberculosis. Besides, emphasis should be given for patients&lt;br&gt;
to undertake cotrimoxazole preventive therapy and to regularly follow their CD4 count.&lt;br&gt;
Keywords: under nutrition, first-line antiretroviral therapy, adult, Ethiopia, HIV&lt;/p&gt;</description>
  </descriptions>
</resource>
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