Journal article Open Access

Prevalence Of Undernutrition And Associated Factors Among Adults Receiving First-Line Antiretroviral Treatment In Public Health Facilities Of Arba Minch Town, Southern Ethiopia

Bilcha Oumer; Negussie Boti; Sultan Hussen; Teklemariam Gultie

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  "DOI": "10.20372/nadre/4444", 
  "abstract": "<p>Introduction: Access to antiretroviral drugs for all infected persons in need is a global<br>\nhealth priority. The primary goals of initiating antiretroviral drugs are to suppress human<br>\nimmunodeficiency virus viral replication and to restore immune function. However, adequate<br>\nnutrition is necessary to manage opportunistic infections and to maintain the immune system.<br>\nTherefore, this study aimed to determine the recent prevalence of undernutrition and<br>\nassociated factors among HIV patients receiving first-line antiretroviral therapy in public<br>\nhealth facilities of Arba Minch town, Gamo zone, Southern Ethiopia.<br>\nMethods: Institution-based cross-sectional study was used among 333 adult patients receiving<br>\nfirst-line antiretroviral therapy at public health facilities of Arba Minch town. A simple<br>\nrandom sampling technique was used to select the study subjects. Data were collected<br>\nthrough interviewer-administered questionnaires. Binary and multivariable logistic regression<br>\nanalyses were used to identify factors associated with undernutrition. A p-value &lt;0.05<br>\nwith a 95% confidence level was used to declare statistical significance.<br>\nResults: The overall prevalence of undernutrition among adult patients receiving first-line<br>\nantiretroviral therapy is 23.72% (95% CI: 19.13&ndash;28.27%). Current substance use<br>\n(AOR=1.83, 95% CI:1.09&ndash;3.08), duration on antiretroviral therapy (AOR=1.87, 95%<br>\nCI:1.06&ndash;3.30), not taking cotrimoxazole preventive therapy (AOR=2.09, 95% CI:1.15&ndash;<br>\n3.82), advanced WHO clinical stages (AOR=5.1, 95% CI: 2.9&ndash;7.7), CD4 count less than<br>\n350 cell/mm3 (AOR=1.83, 95% CI: 1.09&ndash;3.05) and active tuberculosis (AOR=1.89, 95% CI:<br>\n1.02&ndash;3.53) were factors significantly associated with undernutrition among respondents who<br>\nwere enrolled on first-line antiretroviral therapy.<br>\nConclusion: This study shows that the prevalence of undernutrition was high among adult<br>\npatients on first-line antiretroviral therapy. Therefore, this finding shows the need to implement<br>\nnutrition programs to improve the nutritional status of adults living with HIV in the study area.<br>\nThe interventions should emphasise those patients who use the substance, who are in advanced<br>\nWHO clinical stage and have active tuberculosis. Besides, emphasis should be given for patients<br>\nto undertake cotrimoxazole preventive therapy and to regularly follow their CD4 count.<br>\nKeywords: under nutrition, first-line antiretroviral therapy, adult, Ethiopia, HIV</p>", 
  "author": [
      "family": "Bilcha Oumer"
      "family": "Negussie Boti"
      "family": "Sultan Hussen"
      "family": "Teklemariam Gultie"
  "id": "4444", 
  "issued": {
    "date-parts": [
  "title": "Prevalence Of Undernutrition And Associated Factors Among Adults Receiving First-Line Antiretroviral Treatment In Public Health Facilities Of Arba Minch Town, Southern Ethiopia", 
  "type": "article-journal"
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