March 17, 2025 Journal article Open Access

Molalign Aligaz Adisu

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    "description": "<p>Background: Measles remains a global public health concern, despite the availability of effective vaccines. Recent<br>\noutbreaks highlight the need for strong vaccination programs. Since launching both doses, Ethiopia has been<br>\nworking with global health organizations to increase vaccination coverage. However, focusing solely on coverage<br>\noverlooks the importance of timely vaccination. In Ethiopia, despite occasional increases in coverage, measles<br>\noutbreaks persist due to insufficient attention to timeliness. This study aims to assess the timeliness and its<br>\ndeterminants of second-dose measles-containing vaccine uptake in Gondar City to inform efforts to strengthen<br>\nimmunization programs and prevent measles infections.<br>\nMethods: A community-based cross-sectional study was conducted among 618 children aged 24&ndash;36 months.<br>\nParticipants were selected using a two-stage systematic random sampling method from April 25 to May 25.<br>\nStructured questionnaires were administered through interviews, and data were collected using the Kobo toolbox<br>\nand then analyzed using Stata version 17. A binary logistic regression model was utilized to determine factors<br>\nassociated with the outcome, with significance declared at a p-value &lt;0.05. Adjusted odds ratios with 95 %<br>\nconfidence intervals were used to assess the direction and strength of associations.<br>\nResults: Among the total of 618 children, 523 (84.63 %) (95 % CI: 81.77 %&ndash;87.48 %) were vaccinated for MCV2<br>\ntimely (in the national recommended age). Paternal college and above in their education (AOR: 5.84, 95 % CI:<br>\n1.55&ndash;8.18), four or more ANC follow-ups (AOR: 5.84, 95 % CI: 1.55&ndash;8.18), at least two doses of vitamin An<br>\nuptake (AOR: 6.39, 95 % CI: 2.92&ndash;12.59), mothers having high awareness (AOR: 2.04, 95 % CI: 1.05&ndash;3.99), and<br>\nmothers having positive perception (AOR: 4.81, 95 % CI: 2.13&ndash;10.86) to measles vaccination were significant<br>\ndeterminants for timely uptake of the second dose measles-containing vaccine.<br>\nConclusion and recommendations: The timely uptake of the second dose of the measles vaccine in the study area<br>\nwas suboptimal, and efforts should be continued to eradicate measles infection. Paternal educational status, ANC<br>\nfollow-ups, repeated vitamin An uptake, maternal awareness, and perception of measles vaccination were statistically significant determinants for the timely uptake of a second dose of measles-containing vaccine.<br>\nStrengthening maternal and child health services, increasing awareness, and changing mothers&rsquo; perceptions<br>\nabout measles vaccination may increase the timely uptake of MCV2 among children receiving a second MCV<br>\ndose.</p>", 
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    "title": "Timeliness of the second dose of measles-containing vaccine uptake and its determinants among children aged 24\u201336 months in Gondar City, Northwest Ethiopia, 2023: Community-based cross-sectional study design", 
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    "publication_date": "2025-03-17", 
    "creators": [
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        "affiliation": "Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Woldia University, Woldia, Ethiopia", 
        "name": "Molalign Aligaz Adisu"
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