March 17, 2025 Journal article Open Access

Molalign Aligaz Adisu

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        <foaf:name>Molalign Aligaz Adisu</foaf:name>
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            <foaf:name>Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, Woldia University, Woldia, Ethiopia</foaf:name>
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    <dct:title>Timeliness of the second dose of measles-containing vaccine uptake and its determinants among children aged 24–36 months in Gondar City, Northwest Ethiopia, 2023: Community-based cross-sectional study design</dct:title>
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    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#gYear">2025</dct:issued>
    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2025-03-17</dct:issued>
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    <dct:description>&lt;p&gt;Background: Measles remains a global public health concern, despite the availability of effective vaccines. Recent&lt;br&gt; outbreaks highlight the need for strong vaccination programs. Since launching both doses, Ethiopia has been&lt;br&gt; working with global health organizations to increase vaccination coverage. However, focusing solely on coverage&lt;br&gt; overlooks the importance of timely vaccination. In Ethiopia, despite occasional increases in coverage, measles&lt;br&gt; outbreaks persist due to insufficient attention to timeliness. This study aims to assess the timeliness and its&lt;br&gt; determinants of second-dose measles-containing vaccine uptake in Gondar City to inform efforts to strengthen&lt;br&gt; immunization programs and prevent measles infections.&lt;br&gt; Methods: A community-based cross-sectional study was conducted among 618 children aged 24&amp;ndash;36 months.&lt;br&gt; Participants were selected using a two-stage systematic random sampling method from April 25 to May 25.&lt;br&gt; Structured questionnaires were administered through interviews, and data were collected using the Kobo toolbox&lt;br&gt; and then analyzed using Stata version 17. A binary logistic regression model was utilized to determine factors&lt;br&gt; associated with the outcome, with significance declared at a p-value &amp;lt;0.05. Adjusted odds ratios with 95 %&lt;br&gt; confidence intervals were used to assess the direction and strength of associations.&lt;br&gt; Results: Among the total of 618 children, 523 (84.63 %) (95 % CI: 81.77 %&amp;ndash;87.48 %) were vaccinated for MCV2&lt;br&gt; timely (in the national recommended age). Paternal college and above in their education (AOR: 5.84, 95 % CI:&lt;br&gt; 1.55&amp;ndash;8.18), four or more ANC follow-ups (AOR: 5.84, 95 % CI: 1.55&amp;ndash;8.18), at least two doses of vitamin An&lt;br&gt; uptake (AOR: 6.39, 95 % CI: 2.92&amp;ndash;12.59), mothers having high awareness (AOR: 2.04, 95 % CI: 1.05&amp;ndash;3.99), and&lt;br&gt; mothers having positive perception (AOR: 4.81, 95 % CI: 2.13&amp;ndash;10.86) to measles vaccination were significant&lt;br&gt; determinants for timely uptake of the second dose measles-containing vaccine.&lt;br&gt; Conclusion and recommendations: The timely uptake of the second dose of the measles vaccine in the study area&lt;br&gt; was suboptimal, and efforts should be continued to eradicate measles infection. Paternal educational status, ANC&lt;br&gt; follow-ups, repeated vitamin An uptake, maternal awareness, and perception of measles vaccination were statistically significant determinants for the timely uptake of a second dose of measles-containing vaccine.&lt;br&gt; Strengthening maternal and child health services, increasing awareness, and changing mothers&amp;rsquo; perceptions&lt;br&gt; about measles vaccination may increase the timely uptake of MCV2 among children receiving a second MCV&lt;br&gt; dose.&lt;/p&gt;</dct:description>
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