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Prevalence of neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis

Biruk Beletew; Ayelign Mengesha; Mesfin Wudu; Melese Abate


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    "description": "<p><strong>Abstract </strong></p>\n\n<p><strong>Background</strong>: Neonatal hypothermia is a global health problem and a major factor for neonatal morbidity and mortality, especially in low and middle-income countries. Therefore, this systematic review and meta-analysis aimed to assess the prevalence of neonatal hypothermia and its associated factors in Eastern Africa.</p>\n\n<p><strong>Methods:</strong> We used the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to search electronic databases (PubMed, Cochrane Library and Google Scholar; date of last search: 15 October 2019) for studies reporting the prevalence and associated factors of neonatal hypothermia. The data was extracted in the excel sheet considering prevalence, and categories of associated factors reported. A weighted inverse variance random-effects model was used to estimate the magnitude and the effect size of factors associated with hypothermia. The subgroup analysis was done by country, year of publication, and study design.</p>\n\n<p><strong>Results: </strong>A total of 12 potential studies with 20,911 participants were used for the analysis. The pooled prevalence of neonatal hypothermia in East Africa was found to be 57.2% (95%CI; 39.5&ndash;75.0). Delay in initiation of breastfeeding (adjusted Odds Ratio(aOR) = 2.83; 95% CI: 1.40&ndash;4.26), having neonatal health problem (aOR = 2.68; 95% CI: 1.21&ndash;4.15), being low birth weight (aOR =2.16; 95%CI: 1.03&ndash;3.29), being preterm(aOR = 4.01; 95%CI: 3.02&ndash;5.00), and nighttime delivery (aOR = 4.01; 95% CI:3.02&ndash;5.00) were identified associated factors which significantly raises the risk of neonatal hypothermia.</p>\n\n<p><strong>Conclusions:</strong> The prevalence of neonatal hypothermia in Eastern Africa remains high. Delay in initiation of breastfeeding, having a neonatal health problem, being low birth weight, preterm, and nighttime delivery were identified associated factors that significantly raises the risk of neonatal hypothermia.</p>", 
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    "title": "Prevalence of neonatal hypothermia and its associated factors in East Africa: a systematic review and meta-analysis", 
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    "keywords": [
      "Neonates, Hypothermia, Determinants, Eastern Africa, Meta-analysis"
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    "publication_date": "2020-03-03", 
    "creators": [
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        "affiliation": "Woldia University", 
        "name": "Biruk Beletew"
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      {
        "name": "Ayelign Mengesha"
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      {
        "affiliation": "Woldia University", 
        "name": "Mesfin Wudu"
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        "orcid": "0000-0003-1301-4746", 
        "affiliation": "Woldia University", 
        "name": "Melese Abate"
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