Thesis Open Access
ZENAWI HAGOS GUFUE
Background: Globally, stroke appears as a major cause of preventable death and disability.
In Ethiopia, the intra-hospital mortality of stroke is significant and there is scarcity of
epidemiologic data whether there is a difference in the overall survival time between
hypertensive and non-hypertensive adult stroke patients admitted in specialized hospitals.
Objectives: To determine the survival of stroke patients according to their hypertension
status admitted in Ayder Comprehensive Specialized Hospital, Northern Ethiopia from
March 1, 2012 to February 28, 2019.
Methods: A facility-based retrospective cohort study conducted among all cohorts of
confirmed first-ever stroke patients admitted in Ayder Comprehensive Specialized Hospital,
Northern Ethiopia. Kaplan-Meier survival analysis applied to estimate the survival
probability of hypertensive and non-hypertensive first ever stroke patients. Cox proportional
hazards regression model used to determine the adjusted hazard ratio of death for each main
baseline predictor variable, with 95% CI and P-value <0.05 was used to declare statistical
significance. The assumptions of Cox proportional hazards regression model assessed by the
global test, Schoenfeld residuals
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